Recent Articles / Studies

PORTLAND,OR — The more you click, the thinner you can become, if you have a personal health website that tracks your habits, according to a study released Tuesday.
The National Institutes of Health followed 348 people whose Body Mass Index said they were overweight or obese. Each participant for the 30 month study also had to be on medication for high cholesterol or high blood pressure.
The study found that those who clicked on their website faithfully for 24 months maintained the most weight loss.
“The unique part of this intervention was that it was available on the Internet, whenever and wherever people wanted to use it,” said study lead author Kristine L. Funk, a researcher at the Kaiser Permanente Center for Health Research in Portland.
The research started with a group that had to lose weight through weekly meetings where they were weighed, taught to eat well and keep a diary of what they ate.
To continue to the next phase, those people had to lose nine pounds. As a group, they lost an average of 19 pounds.
The participants chosen to continue were provided personal health websites and told to log on once a week to update their weight, amount of exercise and whether or not they were keeping up with food diaries.
Tardy participants were sent an email and received a robocall. Those tardy longer than seven days lost chat privileges with other participants and access to nutrition and exercise experts.
Consistent users who finished the 24 months kept off nine of the 19 average pounds the lost. Those who logged on less often lost an average of five pounds and those who clicked on even less lost an average of just three pounds.
“This study shows that if people use quality weight management websites consistently, and if they stick with their program, they are more likely to keep their weight off,” said study co-author Victor J. Stevens, of the Kaiser Permanente Center for Health Research.
“Keeping weight off is even more difficult than losing it in the first place,” he said, “so the fact that so many people were able to maintain a good portion of their weight loss is very encouraging to us.”
Further Resources:
Body Composition Techniques
The Validity of Bioelectrical Impedance to Predict Human Body Composition
ELG Testing Procedure
Anthropometric ElectroLipoGraphy

A recent article in the Calgary Herald reported on studies linking a lack of sleep to weight gain. As if insomniacs didn’t have enough to keep them awake at night!
The link between sleep deprivation and weight gain was presented at SLEEP 2009, the annual meeting of the Associated Professional Sleep Societies. Scientists studied a group of middle-aged, overweight people to measure whether sleep had any overriding weight-loss effect over dietary changes. During two separate study periods the subjects consumed the same nutritionally balanced diet, but during one period they were allowed to sleep for 8.5 hours, while during the other period they were permitted only 5.5 hours of sleep. Although the subjects lost similar amounts of weight during both periods, they lost less fat (and thus more lean muscle mass) during the sleep-deprived period.
The scientists theorize that sleep deprivation affects hormone secretions, namely increasing the production of ghrelin, which causes an increase of appetite, and decreasing the production of leptin, which slows the sense of satiety brought about by eating. Inother words, sleep deprivation may cause you to feel hungrier and not want to stop eating! (I know I’ve craved a big dish of mac n’ cheese after a sleepless night.)
What to do? The studies suggest not letting your exercise routine fall by the wayside. That will not only help keep your metabolism up, but also keep your energy level stable so that you can (hopefully) reset your internal “snooze” button.

Weight loss and physical activity do a better job of helping people fend off type 2 diabetes than some medications.

  • Historically, nutritional status has been evaluated by various objective measures, including anthropometric (e.g. weight change, arm muscle circumference, triceps skinfold thickness) and laboratory (serum albumin, transferrin assays and nitrogen balancestudies) measurements. Anthropometric methods are not ideal in a clinical setting because they are time-consuming and require well-trained staff. Some of the objective measures such as serum albumin are likely to be influenced by many non-nutritional factors [12-15]. Furthermore, some objective indicators such as serum albumin have long half-lives, thus, assessing changes in the nutritional status over a short period of time is challenging. A less common tool to assess body composition and nutritional status, called Bioelectrical Impedance Analysis (BIA), can overcome some of these challenges. BIA is an easy-to-use, non-invasive, and reproducible technique to evaluate changes in body composition.
    BIA has been validated for the assessment of body composition and nutritional status in a variety of patient populations including cancer [2,5,16-26]. BIA measures body component resistance (R) and reactance (Xc) by recording a voltage drop in appliedcurrent [27]. Resistance is the restriction to the flow of an electric current, primarily related to the amount of water present in the tissues. Reactance is the resistive effect produced by the tissue interfaces and cell membranes [28]. Reactance causes the current to lag behind the voltage creating a phase shift, which is quantified geometrically as the angular transformation of the ratio of reactance to resistance, or the phase angle [29].
    Phase angle reflects the relative contributions of fluid (resistance) and cellular membranes (reactance) of the human body. By definition, phase angle is positively associated with reactance and negatively associated with resistance [29]. Lower phase angles suggest cell death or decreased cell integrity, while higher phase angles suggest large quantities of intact cell membranes [30]. Phase angle has been found to be a prognostic marker in several clinical conditions such as human immunodeficiency virus infection, liver cirrhosis, chronic obstructive pulmonary disease, hemodialysis, sepsis, lung cancer [30-35]. Previously, we had demonstrated the prognostic role of phase angle in advanced colorectal and pancreatic cancer [36,37].
    For more information

A number of biomarkers—detectable changes in genes or proteins that allow for the earlier detection of breast, prostate, colon, lung and other cancers—have been identified through research funded by the National Cancer Institute.
Growing obesity rates in the U.S.
In 1995, obesity prevalence in each of the 50 states was less than 20%. In 2000, 28 states had obesity prevalence rates less than 20%.
In 2005, only 4 states had obesity prevalence rates less than 20%, while 17 states had prevalence rates equal to or greater than 25%, with 3 of those having prevalences equal to or greater than 30% (Louisiana, Mississippi, and West Virginia).
In 2005, only 4 states had obesity prevalence rates less than 20%, while 17 states had prevalence rates equal to or greater than 25%, with 3 of those having prevalences equal to or greater than 30% (Louisiana, Mississippi, and West Virginia).
The states with the highest percentage of obese adults are: Mississippi, Alabama, W. Virginia, Louisiana and Tennessee.
States with the lowest share of obese adults include: Colorado, Vermont and Montana. Hawaii was not included in the report.
While certain regions of the nation fared worse than others, especially in the Southeast, the CDC said that NO state meets the federal government’s goal of a 15% obesity rate for adults by 2010.
—MMarketdata Report, 2009

Each person has an estimated 20,000 to 25,000 genes carrying 3 billion bits of information that constitute an instruction book for the body. When some of these bits become scrambled or otherwise distorted, diseases may result. Research has focused on the variations among people that can be used to create new treatments. (Institute of Health research, PARADE, August 30, 2009).
Predictions for overweight and obese population trend
Experts predict that 75% of U.S. adults will be overweight and 41% will be obese by the year 2015, if current trends continue. Researchers at John Hopkins University in Baltimore examined 20 published studies and reviewed national surveys of weight and behavior to reach these conclusions. The review published in the August 2007 issue of the journal Epidemiological Reviews, found that 16% of U.S. children and adolescents are overweight and 34% are at risk for becoming overweight.
—Nov 2007 Centers for Disease Control and Prevention
Obesity and Body Mass Index
Obesity is defined as a body mass index (BMI) of 30 or greater. BMI is calculated from a person’s weight and height and provides a reasonable indicator of body fatness and weight categories that may lead to health problems. Obesity is a major risk factor for cardiovascular disease, certain types of cancer, and type 2 diabetes.
The study found:
• More than one-third of U.S. adults — over 72 million people — were obese in 2005-2006. This includes 33.3 percent of men and 35.3 percent of women. The figures show no statistically significant change from 2003-2004, when 31.1 percent of men were obese and 33.2 percent of women were obese.
• Adults aged 40-59 had the highest obesity prevalence compared with other age groups. Approximately 40 percent of men in this age group were obese, compared with 28 percent of men aged 20-39, and 32 percent of men aged 60 and older. Among women, 41 percent ofthose aged 40-59 were obese compared with 30.5 percent of women aged 20-39. Women aged 65 and older had obesity prevalence rates comparable with women in the 20 to 39 age group.
• There were large race-ethnic disparities in obesity prevalence among women. Approximately 53 percent of non-Hispanic black women and 51 percent of Mexican-American women aged 40-59 were obese compared with about 39 percent of non-Hispanic white women of the same age. Among women 60 and older, 61 percent of non-Hispanic black women were obese compared with 37 percent of Mexican-American women and 32 percent of non-Hispanic white women.

A new study finds obese people have 8 percent less brain tissue than normal-weight individuals. Their brains look 16 years older than the brains of lean individuals, researchers said today.
Those classified as overweight have 4 percent less brain tissue and their brains appear to have aged prematurely by 8 years.
The results, based on brain scans of 94 people in their 70s, represent “severe brain degeneration,” said Paul Thompson, senior author of the study and a UCLA professor of neurology.
“That’s a big loss of tissue and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer’s and other diseases that attack the brain,” said Thompson. “But you can greatly reduce your risk for Alzheimer’s, if you can eat healthily and keep your weight under control.”
The findings are detailed in the online edition of the journal Human Brain Mapping.
Dietary Supplement Influences Body Composition
More than one billion human adults worldwide are overweight and, therefore, are at higher risk of developing cardiovascular diseases, diabetes, and a variety of other chronic perturbations. Many believe that use of natural dietary supplements could aid in the struggle against obesity. So-called “starch blockers” are listed among natural weight loss supplements. Theoretically, they may promote weight loss by interfering with the breakdown of complex carbohydrates thereby reducing, or at least slowing, the digestive availability of carbohydrate-derived calories and/or by providing resistant starches to the lower gastrointestinal tract.
The study found:
After 30 days, subjects receiving Phaseolus vulgaris extract with a carbohydrate-rich, 2000- to 2200-calorie diet had significantly greater reduction of body weight, BMI, fat mass, adipose tissue thickness, and waist,/hip/ thigh circumferences while maintaining lean body mass compared to subjects receiving placebo.
The results indicate that Phaseolus vulgaris extract produces significant decrements in body weight and suggest decrements in fat mass in the face of maintained lean body mass.
For more information, read the extract here.
Celleno L, Tolaini MV, D’Amore A, Perricone NV, Preuss HG. A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women. Int J Med Sci 2007; 4:45-52.

Men’s need for hormone replacement has been undervalued and criticized by general medical providers and lawmakers.
Men develop age related conditions that are reflective of hormone deficiencies that are specific to men. The fact that the patient is a male, should not minimize the value of the problems middle aged men face. For more information

Our lipotropic injections consist of a proprietary blend of Methionine, Inositol, Choline, amino acids and B complex vitamins. Combined these lipotropic nutrients encourage the export of fat from the liver. Lipotropics are necessary for the maintenance of a healthy liver as well as burning the exported fat for additional energy. For more information

Human Chorionic Gonadotrophin (hCG) is a poly peptide hormone found in men and women. Women secrete large amounts of hCG during pregnancy and men secrete large amounts during puberty For more information

Thrive Health Solutions offers many physician prescribed and medically supervised Testosterone Therapy programs helping patients enter a cost effective and comprehensive testosterone treatment program designed to treat adult men over the age of 35 suffering from symptoms and problems associated with low testosterone, hypogonadism and andropause also known as “male menopause”.For more information

Vitamin B-12is a water soluble vitamin which helps maintain healthy nerve cells and red blood cells. It functions as a methyl donor and works with folic acid in the synthesis of DNA and red blood cells and is vitally important in maintaining the health of the insulation sheath that surrounds nerve cells.For more information

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